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Image Search Results
Journal: Cancer Cell International
Article Title: Dysregulation of pseudouridylation in small RNAs contributes to papillary thyroid carcinoma metastasis
doi: 10.1186/s12935-024-03482-3
Figure Lengend Snippet: Effects of PUS7 on miRNA, pre-miRNA and tsRNA ψ modification. A . Clinical index of 9 paired PTCs and paracancerousous tissues. B . Workflow of Arraystar Human Pseudouridine (ψ) small RNA modification microarray analysis. C . PCA plot comparing the PTC group and the paracancer group. D . The number of miRNAs, pre-miRNAs, and tsRNAs identified in PTCs and paracancerous tissues (Left), and the number of differentially modified miRNAs, pre-miRNAs, and tsRNAs found in PTCs (Right). E-F . Volcano plot ( E ) and heatmap ( F ) of diff-modified miRNAs, pre-miRNAs, and tsRNAs. G . The top two differentially modified pre-miRNAs. H . MeRIP-qPCR validation of ψ modification of pre-miR-8082 and pre-miR-152. Data are presented as mean ± SD. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001
Article Snippet: B . Workflow of
Techniques: Modification, RNA modification, Microarray, Biomarker Discovery
Journal: bioRxiv
Article Title: Cannabinoids shift the basal ganglia miRNA m 6 A methylation profile towards an anti-inflammatory phenotype in SIV-infected Rhesus macaques
doi: 10.1101/2024.10.11.614514
Figure Lengend Snippet: A) Percent mature and star miRNAs with m 6 A methylation marks. B-D) m 6 A methylation patterns in each treatment group. E-G) Heatmap of m6A methylation profile versus miRNA abundance.
Article Snippet: We have completed the
Techniques: Methylation
Journal: bioRxiv
Article Title: Cannabinoids shift the basal ganglia miRNA m 6 A methylation profile towards an anti-inflammatory phenotype in SIV-infected Rhesus macaques
doi: 10.1101/2024.10.11.614514
Figure Lengend Snippet: A) Neuroinflammation network molecules associated with the with miRNAs with m6A hypomethylation (left) or hypermethylation (right).
Article Snippet: We have completed the
Techniques:
Journal: Journal of Cancer
Article Title: Modulation of Wnt Activity and Cell Physiology by Butyrate in LT97 Microadenoma Cells
doi: 10.7150/jca.8569
Figure Lengend Snippet: Venn diagrams of microarray data. (A) Venn diagram for “within treatment” comparison of differentially expressed genes in mock or butyrate treatments across cell lines (>3Fold, 9,096 probes). 99 intersection probes are differentially expressed in opposite directions. 2,685 intersection probes are differentially expressed in the same direction. (B) Venn diagram for “within cell lines” comparison of differentially expressed genes in mock treated control (Ctrl) vs. butyrate (NaB) treatments of two cell lines (>3Fold, 8,335 probes). 165 intersection probes are differentially expressed in opposite directions. 1,986 intersection probes are differentially expressed in the same direction.
Article Snippet: After treatment with or without 5 mM butyrate for 17.5 hr, cells were washed with 1 x PBS, scraped into PBS and pelleted; the pellets were snap frozen in liquid nitrogen and sent to
Techniques: Microarray, Comparison, Control